The comedian opened up about the “lonely disease” and the stigma associated with periods in an intimate interview with CBS News medical contributor Dr. David Agus for the new Paramount+ original docuseries “The Checkup with Dr. David Agus.” The 30-minute episode will be available to stream starting Tuesday, Dec. 13.
Schumer said she’s been experiencing severe pain for decades since she first got her period.

Endometriosis is a disorder that occurs when the uterine lining grows outside of the uterus in places like the fallopian tubes, ovaries or other tissue around the pelvic area, which can cause painful cramping during your period, Dr. Agus explained in the episode. In addition to painful periods, other common symptoms of endometriosis include pain during intercourse, painful urination or bowel movements, cysts, infertility and more, the Mayo Clinic says.
Last year, Schumer had a hysterectomy, a removal of the uterus, to help treat her endometriosis. She also underwent an appendectomy, explaining in an Instagram post at the time that doctors found a tumor in her “endo-ravaged appendix.”
Schumer has used her social media platforms to reassure others experiencing aches or pains during their menstrual cycles that their concerns are valid.
Schumer said the scars from the surgeries are worth it because she felt immediate relief.
In 2018, when Schumer was pregnant with her son Gene, she was hospitalized with hyperemesis, a severe type of morning sickness.
Schumer’s son, who is now 3 years old, was hospitalized in early November for the respiratory syncytial virus (RSV) but has since recovered.